Tumour necrosis factor-α, adenosine deaminase and nitric oxide levels in cattle babesiosis before and after treatment

Kontaş T., Salmanoǧlu B.

Bulletin of the Veterinary Institute in Pulawy, vol.50, no.4, pp.485-487, 2006 (SCI-Expanded, Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 4
  • Publication Date: 2006
  • Journal Name: Bulletin of the Veterinary Institute in Pulawy
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.485-487
  • Keywords: Adenosine deaminase, Babesiosis, Cattle, Nitric oxide, Tumour necrosis factor-α
  • Hatay Mustafa Kemal University Affiliated: Yes

Abstract

Changes in serum tumour necrosis factor-α (TNF-α), nitric oxide (NO), and adenosine deaminase (ADA) levels in cattle babesiosis before and after treatment with diminazene aceturate were determined. Before treatment, TNF-α, NO, and ADA levels were found to be 71.93 pg/ml, 50.03 μmol/L, 70.18 IU/L, respectively. These levels were significantly higher than those in the control group. After the treatment, the levels of the compounds significantly decreased. In conclusion, besides TNF-α and NO, ADA can also be a predictive and sensitive parameter in the diagnosis and prognosis of babesiosis.