Research Information System
International Ophthalmology, vol.42, no.4, pp.1289-1297, 2022 (SCI-Expanded, Scopus)
Purpose: To evaluate and compare the effects of different intraocular tamponade agents on lens density after vitrectomy. Methods: The participating patients were divided into four groups according to the tamponade agent used: a sulfur hexafluoride (SF6) group, a perfluoropropane (C3F8) group, a silicone oil group, and a no tamponade group. Lens density measurements were performed preoperatively and two weeks, one month, and three months postoperatively using a Pentacam HR device with a Scheimpflug camera. The postoperative values were compared with the preoperative baseline values, also the values were compared between the four groups. Results: The study included 82 eyes (82 patients). In the SF6 group, lens density significantly increased in all zones two weeks and one and three months postoperatively (all P <.05). In the C3F8 group, lens density significantly increased in all zones three months postoperatively (all P <.01). In the silicone oil group, the zone 1, zone 2, and average lens density (ALD) value significantly increased one and three months postoperatively (all P <.05). In the no tamponade group, the zone 1, zone 2, and ALD values significantly increased three months postoperatively (all P <.05). There were no significant differences between the four groups in any zone either preoperatively or postoperatively (all P >.05). Conclusions: Although increases in lens density were observed earlier in the tamponade groups than in the no tamponade group, between the groups over the follow-up period were no differences. We need the development of new surgical methods and materials to prevent post-vitrectomy lens damage in the future.