Akademik Veri Yönetim Sistemi
Türk Kardiyoloji Derneği Arşivi, cilt.47, sa.6, ss.440-448, 2019 (Scopus)
Objective: The aim of this research was to investigate the re- lationship between atrial fibrillation (AF) recurrence and sec- ond generation cryoballoon ablation (CBA) procedural pa- rameters in patients with non-valvular paroxysmal AF (PAF).Methods: A total of 131 patients with a PAF diagnosis who underwent second-generation CBA (59 male; mean age: 55.2±10.6 years) were enrolled. Recurrence was defined as the detection of AF on a 12-lead electrocardiography (ECG) recording, or an attack lasting at least 30 seconds observed on Holter ECG records. CBA procedural data and echocar- diographic findings were recorded and compared.Results: After 1 year of follow-up, AF recurrence was de- tected in 27 patients. Patients with recurrence were older and had higher rates of hypertension and diabetes (p<0.05 for both). Left atrial diameter, left atrial volume (LaV), left atrial volume index, and the averaged warming angle (cal- culated by combining lowest temperature point and balloon temperature at 20°C point) were significantly higher in the recurrence group. Balloon warming time was significantly longer in the non-recurrence group (p<0.001). In binary logistic regression analysis, the averaged warming angle (odds ratio [OR]: 1.559, 95% confidence interval [CI]: 1.342–1.811; p<0.001) and LaV (OR: 1.063, 95% CI: 1.028–1.100;p<0.001) were found to be independent parameters for pre- dicting recurrence. The cutoff value of the warming angle obtained with ROC curve analysis was 50° for the prediction of recurrence (sensitivity: 94.3%, specificity: 88.5%, area under the curve: 0.909; p<0.001). The cutoff value of LaV obtained by ROC curve analysis was 53.5 for prediction of recurrence (sensitivity: 77.8%, specificity: 74.5%; p<0.001).Conclusion: Measurement of balloon warming angle during CBA and increased LaV may predict the AF recurrence.