Akademik Veri Yönetim Sistemi
Viral Hepatitis Journal, cilt.26, sa.2, ss.56-60, 2020 (ESCI)
Objectives: The treatment duration and response of chronichepatitis C (CHC) are closely related to the genotypes of hepatitisC virus (HCV). This study aimed to determine the genotypedistributions among CHC patients in the Hatay province of Turkey.Materials and Methods: In this study, demographic data of 589patients who received a therapy for CHC at the infectious diseasesand gastroenterology clinics between June 2016 and May 2019were retrieved from the hospital information system and medicalcharts of the patients and were retrospectively reviewed.Results: The most common HCV genotype in our study wasgenotype 1b (66.9%), followed by genotype 2 (10.5%), genotype 1a(7.3%), genotype 4 (7.1%), genotype 3 (7%), and mixed genotype(1.2%). Six of the mixed genotypes were identified as 1b+4, whileone was 1a+3. There was a statistically significant differencebetween females and males with regards to the HCV genotypes(p<0.001). Patients with genotype 1b tended to be older, whilepatients with genotypes 3 and 4 tended to be younger.Conclusion: Genotype 1b is the most common HCV genotypein Hatay province, and it is followed by genotypes 2, 1a, 4 and 3.Compared to the studies conducted in previous years in Turkey,our study identified a lower rate for genotype 1b, along with anincrease in the distribution rates of the other genotypes. Monitoringthe changes in HCV genotype distribution is of vital importance todevelop effective strategies in the treatment of HCV