Effects of Oxidative Stress-Related Major Molecular Parameters on Milk Composition in Weaning Period of Damascus Goats Sütten Kesim Dönemindeki Damascus Keçilerinde Oksidatif Stresle İlişkili Majör Moleküler Parametrelerin Süt Bileşimi Üzerine Etkileri

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ÖZKAN H., Dalkiran S., KARAASLAN İ., KAYA U., Çamdeviren B., YÜKSEL M., ...Daha Fazla

Kafkas Universitesi Veteriner Fakultesi Dergisi, cilt.28, sa.3, ss.371-377, 2022 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.9775/kvfd.2022.27101
  • Dergi Adı: Kafkas Universitesi Veteriner Fakultesi Dergisi
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.371-377
  • Anahtar Kelimeler: COX-2, Damascus goat, Gene expression, NFE2L2, Weaning in goats
  • Hatay Mustafa Kemal Üniversitesi Adresli: Evet

Özet

The weaning process in goat breeding is applied in various methods depending on the breeding administration. In this study, blood and milk samples have been collected from Damascus goats at the weaning day (postpartum 105th day-weaned day) and a week later (post-weaned day). In addition to determining cortisol and MDA in plasma, COX-2 and NFE2L2 activities have been investigated both mRNA and protein levels from leucocytes and plasma. Compositional parameters of milk have also been analyzed and the possible relations between studied parameters have been investigated. While expression levels of COX-2 and SCC of milk decreased, pH of milk was increased in post-weaned day samples. Th e MDA, FFDM, protein, lactose and freezing point were decreased in the post-weaned day. Milk fat was negatively correlated with NFE2L2, and milk protein had positively correlated with SCC and FFDM. On the other hand, lactose was positively correlated with FFDM and protein. In addition, most of the compositional parameters positively correlated with a freezing point; they were negatively correlated with electrical conductivity. According to the results obtained from the study, it is thought that the decrease in milk fat in goats may be an indicator of increased oxidative stress in lactating goats due to the increase in NFE2L2 protein, which has a central role in the antioxidant response.