QTc dispersion and P-wave dispersion during migraine attacks

Duru M., Melek I., Seyfeli E., Duman T., Kuvandik G., KAYA H., ...More

Cephalalgia, vol.26, no.6, pp.672-677, 2006 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 6
  • Publication Date: 2006
  • Doi Number: 10.1111/j.1468-2982.2006.01081.x
  • Journal Name: Cephalalgia
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.672-677
  • Keywords: Autonomic nervous system, Electrocardiography, Migraine attacks, P-wave dispersion, QTc dispersion
  • Hatay Mustafa Kemal University Affiliated: Yes

Abstract

The aim of this study was to investigate increase of QTc dispersion and P-wave dispersion during migraine attacks. Fifty-five patients (16-65 years of age, 49 women, six men) with migraine were included in our study. Heart rate, QTc interval, maximum and minimum QTc interval, QTc dispersion, maximum and minimum P-wave duration and P-wave dispersion were measured from 12-lead ECG recording during migraine attacks and pain-free periods. ECGs were transferred to a personal computer via a scanner and then used for magnification of ×400 by Adobe Photoshop software. Maximum QTc interval (454 ± 24 ms vs. 429 ± 23 ms, P < 0.001), QTc interval (443 ± 26 ms vs. 408 ± 22 ms, P < 0.001) and QTc dispersion (63 ± 18 ms vs. 43 ± 14 ms, P < 0.001) were found significantly higher during migraine attacks compared with pain-free periods. Maximum P-wave duration (107 ± 11 ms vs. 100 ± 11 ms, P < 0.001) and P-wave dispersion (45 ± 13 ms vs. 35 ± 13 ms, P < 0.001) were found higher during migraine attacks than pain-free periods. We concluded that migraine attacks are associated with increased QTc and P-wave dispersion compared with pain-free periods. © Blackwell Publishing Ltd. 2006.