The prevalence of silent cerebral infarct in patients with sickle cell disease Orak hücre hastalarinda sessiz serebral enfarkt sikliǧi
Turk Beyin Damar Hastaliklar Dergisi, cilt.14, sa.3, ss.79-82, 2008 (Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 14 Sayı: 3
- Basım Tarihi: 2008
- Dergi Adı: Turk Beyin Damar Hastaliklar Dergisi
- Derginin Tarandığı İndeksler: Scopus
- Sayfa Sayıları: ss.79-82
- Anahtar Kelimeler: Brain, Magnetic resonance, Sickle cell disease, Silent infarct
- Hatay Mustafa Kemal Üniversitesi Adresli: Evet
Özet
Objective: To determine the prevalence of silent cerebral infarct and abnormal brain magnetic resonance imaging (MRI) findings in patients with sickle cell disease (SCD). Materials and methods: Fifty-two brain MR images of the asymptomatic patients with SCD have been reviewed retrospectively. The abnormal MRI findings were recorded. Results: Forty-four of the 52 patients with SCD were homozygous (S/S) and remaining 8 heterozygous (S/ßthal) for SCD. Twelve (27.2%) of the 44 patients with S/S and 2 (25%) of the 8 patients with S/ßthal had silent infarcts. Ten (22.7%; 7 diffuse cerebral, 2 focal cerebral and 1 cerebellum) of the 44 S/S patients demonstrated atrophy. None of the 8 patients with S/ßthal had cerebral atrophy. Conclusion: Patients with SCD living in Hatay demonstrated a high rate of silent cerebral infarct and cerebral atrophy. These findings concur with the results of the literature.