Bioefficacyof Laurel<i> (Laurus</i><i> nobilis</i> L.) Esse of Pontastacus leptodactylus Lipopolysaccharide-Induced Inflammation in Japanese Quails ntials Oil on

İŞGÖR M. M., ALAŞAHAN S., KÜÇÜKGÜL A., Kanat O., Hark B. D., ÖNEL S. E.

REVISTA CIENTIFICA-FACULTAD DE CIENCIAS VETERINARIAS, cilt.35, sa.2, 2025 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 2
  • Basım Tarihi: 2025
  • Doi Numarası: 10.52973/rcfcv-e35578
  • Dergi Adı: REVISTA CIENTIFICA-FACULTAD DE CIENCIAS VETERINARIAS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, CAB Abstracts, Food Science & Technology Abstracts, Veterinary Science Database
  • Hatay Mustafa Kemal Üniversitesi Adresli: Evet

Özet

The potential use of natural plants and essential oils as feed ABSTRACT additives in poultry farming is a popular research area. In the presentedstudy, the effects of laurelessentialoilon me hoate (DMT) pes icid is one of the ch micals u ed to growthandfeedconversion performances, slaughter-carcass otect some agricultural areas from harmfu organisms DMT characteristicsoxidativestressindexandhistopathological sidues releas d directl or in irectl to he environment auseseriousproblems innatureDMTresiduesmixedwith the parameters in Japanese quails in LPS-induced inflammation quaticenvironmentadverselyaffect aquatico ganismsand model were investigated. The study groups were established as Control (C), laurelessential oil (LEO) group, lipopolysaccharide is effect is carred to humans through the ood chain In this udy, oxidative stress responses induced by DMT pestic de in (LPS) group, laurel essential oil together with lipopolysaccharide (LEO+LPS) group. The live weights on the 19th, 26th and 33rd were investiga ed. Forhis purpose, days were higher in the LEO+LPS and in the LEO group on the xidative sress and antoxdan parametersTh obarbituric acid 36th day. Feed utilization was the worst in the LPS and the best in theLEOgroup. Non-eviscerated carcass yield was lower active sub tances TBARS), Glutath one (G H) Superoxide insmutatheeLPS(SOD),groupcatalasecompared(CATto) theandglutathcontrol,oneandtheperoxidasegizzard weight washigherin theLEO,LEO+LPS andLPS groups. The PX) ca sed by dimethoate (DMT) pesticide inOSIvaluewasobservedas highest in the LPS group and the 17 5 35, and 70 mgL-concentrations at 24 and 96 hours ere investigated Results were determined using ELISA kits. lowest in the LEO group. In addition, OSI value in the LEO group reduced importantly comparing with LEO+LPS group. Liver OSI o significant difference was observed in GSH levels and SOD values did not show any significant difference in all groups. Histopathologically, no significant difference was observed, tivities compared to con rol. Statistcally signifiant dfferences ere obse vedbetweendecreasesiCAT and GPx ctivities and in terms of fatty liver, congestion, degeneration necrosis and cellcreasesinfiltratinion.TBARSThelevels.additionSPSSof24.0laurelpackageincreasedprogramdegeneratone-wayion, NOVA(Dncan005) was usedin heevaluationofbochemical necrosis and desquamation and cell infiltration in the lamina nalyzes As a re ultt was determ nedthatDMTcausedoxdative epithelialis in the intestine. In the intestines, cell infiltration ress ormation n and aus dchanges in enzy e was significantly increased in the LPS group compared to the control group. In addition, eosinophilic accumulations ctviti s were detected in the brain in the LPS group. As a result, it ey words: Dime hoa e oxdative was determined that laurel essential oil improved live weight and feed conversion rate,made a significant contribution to stress antioxidant,biomarkers balancing the oxidant-antioxidant capacity ratio, and showed significant bioactivity, especially in terms of turning the negative effect of LPS into positive.