Akademik Veri Yönetim Sistemi
Turkderm Deri Hastaliklari ve Frengi Arsivi, cilt.43, sa.2, ss.58-60, 2009 (Scopus)
Background and Design: The sympathetic skin response (SSR) is a electrophysiological test used as an index of sudomotor sympathetic function. The aim of this study was to evaluate possible sympathetic nervous system dysfunction in vitiligo patients with the sympathetic skin response. Material and Method: Sympathetic skin response was studied in 26 patients (20 female and 6 male) with clinical definitely generalized vitiligo and 23 healthy controls (18 female and 5 male). This study was performed in a semi-darkened room while the patients were in supine position. SSR recordings in all of the subjects were performed by a Medelec electroneuromyograph. Results: The average age of patients and controls were 30.6±12.8 and 29.7±10.5, respectively. No demographic differences existed statistically between patients and controls (p>0.05). The mean latency of SSR in vitiligo patients [mean SSR latency in patients, 1.48±0.58 ms vs controls, 1.52±0.46 ms (p=0.944)] was not significantly different compared with the controls. The mean amplitude of SSR in vitiligo patients (mean SSR amplitude in patients, 3.83±2.95 mV vs controls, 5.09±3.60 mV) was smaller compared with the controls, but this difference was not significant (p=0.100). Conclusion: We conclude that vitiligo has no significant effect on the sympathetic skin response.