Isotretinoin treatment in patients with acne vulgaris: Does it impact muscle strength, fatigue, and endurance?

Yildizgoren M. T., Rifaioglu E. N., Demirkapi M., Ekiz T., Micoogullari A., ŞEN T., ...Daha Fazla

Cutis, cilt.96, sa.1, ss.33-36, 2015 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 96 Sayı: 1
  • Basım Tarihi: 2015
  • Dergi Adı: Cutis
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.33-36
  • Hatay Mustafa Kemal Üniversitesi Adresli: Evet

Özet

The objective of this study was to evaluate the effects of isotretinoin on muscle strength, fatigue, and endurance in patients with acne vulgaris. The study included 27 patients with acne vulgaris who underwent treatment with isotretinoin as well as 26 control patients for comparison. Participants in the treatment group received oral isotretinoin 0.5 mg/kg once daily for 1 month followed by an increased dose of 1 mg/kg once daily for 2 months. Isokinetic measurements were obtained from the hamstrings and quadriceps on the nondominant side of the body at baseline and 3-month follow-up using an isokinetic dynamometer. Results indicated that systemic isotretinoin did not significantly alter muscle strength, fatigue, and endurance.