Reference values of serum cystatin-C for full-term and preterm neonates in Istanbul

Dorum S., Silfeler I., Dorum B. A., Silfeler D. B., Canbak Y., Say A.

Indian Journal of Pediatrics, cilt.79, sa.8, ss.1037-1042, 2012 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 79 Sayı: 8
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1007/s12098-011-0655-y
  • Dergi Adı: Indian Journal of Pediatrics
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1037-1042
  • Anahtar Kelimeler: Cystatin C, GFR, Neonate
  • Hatay Mustafa Kemal Üniversitesi Adresli: Evet

Özet

Objective To determine the level and distribution of Cystatin C values in full-term and preterm healthy neonates for the purpose of diagnosis and follow-up of renal diseases of the neonates. Methods Eighty-eight newborn infants, including 55 preterm and 33 term born in the authors' hospital having no urinary tract pathology, symptoms or signs during prenatal and postnatal follow-up, were studied, Results There were 25 neonates born between gestational wk of 28 and 32 (Group 1), 30 neonates born between gestational wk of 33-36 (Group 2) and 33 neonates born after gestational wk of 37 (Group 3). Average cystatin C values were determined to be 1.41 mg/l, 1.22 mg/l and 1.21 mg/l for Group 1, Group 2 and Group 3, respectively. Conclusions Evalution of cystatin C can be effective for follow-up of renal pathologies, because it is not affected by gender, body weight and muscle mass and has a constant production rate. © Dr. K C Chaudhuri Foundation 2011.