Congenital extraneural hemangioblastoma in a lamb

Yaman T., Karasu A., UYAR A., Kuşçu Y., Keleş Ö. F.

Journal of Veterinary Diagnostic Investigation, cilt.31, sa.2, ss.263-266, 2019 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 2
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1177/1040638719830464
  • Dergi Adı: Journal of Veterinary Diagnostic Investigation
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.263-266
  • Anahtar Kelimeler: CD45, glial fibrillary acidic protein, hemangioblastoma, lambs, neuron-specific enolase
  • Hatay Mustafa Kemal Üniversitesi Adresli: Evet

Özet

A 1-mo-old Ivesi male lamb was presented with 2 large red masses on the skin of the left ear. The tumors were removed using gentle dissection and submitted for histologic evaluation. The tumors consisted of numerous thin-walled capillaries lined by endothelial cells and nests of stromal cells. Immunohistochemically, the endothelial cells were positive for CD45, and the stromal cells were positive for neuron-specific enolase. GFAP-positive cells were occasionally present within the tumor. Endothelial and stromal cells were negative for S100, CD34, CD31, and factor VIII–related antigen. The tumor had strong gross, microscopic, and immunohistochemical similarities with human extraneural hemangioblastoma.