Akademik Veri Yönetim Sistemi
Indian Journal of Pharmaceutical Sciences, cilt.83, sa.2, ss.238-246, 2021 (SCI-Expanded)
This study aims to determine the chemical and physical composition and antibacterial activity of glasswort. Soxhlet extraction of S. europaea was performed using Hexane and analyzed by Gas chromatography-mass spectrometry. Alpha-tocopherol content was analysed by using Liquid chromatography with tandem mass spectrometry. The elemental analysis was investigated by inductively coupled plasma mass spectrometry. The crystallographic texture and composition of powder samples were determined by X-ray diffraction. The Minimum Inhibition Concentrations and inhibition zones extracts of S. europaea were performed by spectrophotometric broth microdilution and disc diffusion methods, respectively, against 4 bacteria (Escherichia coli, Klebsiella pneumonia, Bacillus subtilis, Staphylococcus aureus) and 2 fungi (Candida albicans, C. parapsilosis). Alpha-tocopherol quantity and oil content of S. europaea were found to be 2.1±0.3mg/100 g and 15.15 %, respectively. The detected minerals were also found as Na 447, Mg 51.98, K 45.86, Ca 14.27 ppm. The highest minimum inhibition concentration was 0.9 mg/mL against E. coli in methanol extract (p<0.05). The highest mean inhibition zones diameter was 3.8 mm for methanol extracts against B. subtilis (p<0.05). As a result, the extract and oil of S. europaea can be used as potential bioactive and antimicrobial agents for pharmaceutical and cosmetics applications.