Serum adiponectin and resistin levels in patients with obsessive compulsive disorder

Ari M., Ozturk O. H., Bez Y., Arica S., Can Y., Erduran D.

Journal of Affective Disorders, vol.136, no.3, pp.979-982, 2012 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 136 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.1016/j.jad.2011.07.029
  • Journal Name: Journal of Affective Disorders
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.979-982
  • Keywords: Adiponectin, Anxiety, Obsessive compulsive disorder, Resistin
  • Hatay Mustafa Kemal University Affiliated: Yes

Abstract

We aimed to investigate the changes in serum adiponectin and resistin levels in patients with obsessive compulsive disorder and control groups. The serum adiponectin and resistin levels of 29 patients (16 females, 13 males) with obsessive compulsive disorder and weight, age and sex-matched 31 healthy controls (17 females, 14 males) were determined. Yale-Brown Obsessive Compulsive Scale (Y-BOCS) was applied to all groups. ELISA method was used to measure adiponectin and resistin levels. The mean adiponectin level was 11.92 ± 2.04 ng/ml and resistin level was 13.23 ± 2.78 ng/ml in obsessive compulsive disorder group, while it was 18.81 ± 5.24 ng/ml and 8.17 ± 2.53 ng/ml in control group. Changes in plasma adiponectin and resistin levels in obsessive compulsive disorder may have implications about possible cardiovascular and metabolic abnormalities seen in obsessive compulsive patients. © 2011 Elsevier B.V. All rights reserved.