Effect of 1-deamino 8-d-arginine vasopressin spray on nasal cytology and mucociliary clearance in patients with nocturnal enuresis
International Journal of Pediatric Otorhinolaryngology, cilt.70, sa.11, ss.1919-1922, 2006 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 70 Sayı: 11
- Basım Tarihi: 2006
- Doi Numarası: 10.1016/j.ijporl.2006.06.019
- Dergi Adı: International Journal of Pediatric Otorhinolaryngology
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1919-1922
- Anahtar Kelimeler: DDAVP spray, Nasal mucosa, Nocturnal enuresis, Vasopressin
- Hatay Mustafa Kemal Üniversitesi Adresli: Evet
Özet
Objective: To determine any possible adverse effect of 1-deamino 8-d-arginine vasopressin (DDAVP) spray on nasal cytology and mucociliary clearance in patients with nocturnal enuresis. Methods: Twenty-two children aged 6-16 enrolled in the study. Epithelial surface cells samples were taken from the nasal mucosa and mucociliary clearance time was calculated before and 1 and 6 months after administration of DDAVP spray. Results: No qualitative changes in the epithelial surface cells and mucociliary clearance time were observed at 1 and 6 months after therapy. Conclusion: Based on the findings of the present study, DDAVP spray can be used for 6 months in children without apparent risk of damage to the epithelial surface cells and mucociliary clearance time. © 2006 Elsevier Ireland Ltd. All rights reserved.