Akademik Veri Yönetim Sistemi
Kafkas Üniversitesi Veteriner Fakültesi Dergisi, cilt.4, sa.1-2, ss.21-30, 1998 (Hakemli Dergi)
The induction of dietary hypersentitivity using selected antigen was used to establish an experimental model of feline infammatory bowel disease (IBD). Following the introduction of novel dietary antigens macroscopic and microscopic examination of the intestinal mucosa by endoscopy, bacteriological culture of endoscopically collected small intestinal wuice and histological examination of endoscopically obtained intestinal biopsies were carried out. The numbers of intraepithelial lymphocytes (IEL) and the relative numbers of plasma cells (IgG, IgM, IgA), T cells (CD4+, CD8+, CD5+) and MHC class 11+ cells in the lamina propria were counted. Villus width was also measured. Measurement of the hydrogen concentration in breath was used to diagnose small intestinal bctarial overgrowth after administration lactulose and malabsorption after administration of xylose. Intestinal permeability was determined from the percentage urinary recovery of the disaccharide, lactulose, and the monosaccharide, mannitol, after administration of these sugars as an isotonic solution. By day 165, histologically some villi were and wider, and there was an increase in the number of neutrophils and macrophages in the lamina propria of the cats fed ovalbumin.