Markers of inflammation as determinants of mortality in intensive care unit patients

Kuvandik G., UÇAR E., Borazan A., Aydemir S., Ilikhan S., Sekitmez N., ...Daha Fazla

Advances in Therapy, cilt.24, sa.5, ss.1078-1084, 2007 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 24 Sayı: 5
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1007/bf02877714
  • Dergi Adı: Advances in Therapy
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1078-1084
  • Anahtar Kelimeler: C-reactive protein, Erythrocyte sedimentation rate, Hemoglobin, Intensive care, Leukocyte count, Mortality rate, Platelet count
  • Hatay Mustafa Kemal Üniversitesi Adresli: Evet

Özet

In this study, the investigators explored the relationship between mortality rate and serum levels of C-reactive protein (CRP), erythrocyte sedimentation ratio (ESR), albumin, and hemoglobin, leukocyte, and platelet counts of patients at the time of first admission to the intensive care unit (ICU). A total of 123 patients were admitted to 2 different ICUs. In the emergency departments, serum levels of CRP, ESR, and albumin and hematologic parameters of 81 patients who died and 42 patients who survived were compared. A Student t test and the χ 2 test were used for statistical analyses. Mean CRP and ESR levels and leukocyte counts were higher in nonsurvivor than in survivor groups (P<.001 for all). Additionally, serum CRP and ESR elevations and leukocyte counts were determined to be individually related to mortality (P<.001, P<.05, and P<.05, respectively). The investigators concluded that initial serum levels of CRP and ESR and leukocyte counts can be used as determinants of mortality in ICU patients. ©2007 Health Communications Inc.