Relation of angiographic thrombus burden with electrocardiographic grade III ischemia in patients with ST-segment elevation myocardial infarction

Kurt M., Karakas M. F., Buyukkaya E., Akçay A. B., Sen N.

Clinical and Applied Thrombosis/Hemostasis, vol.20, no.1, pp.31-36, 2014 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.1177/1076029613476340
  • Journal Name: Clinical and Applied Thrombosis/Hemostasis
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.31-36
  • Keywords: grade III ischemia, ST-elevation myocardial infarction, thrombus burden
  • Hatay Mustafa Kemal University Affiliated: Yes

Abstract

Background: We aimed to investigate the association between electrocardiographic (ECG) grade III ischemia and angiographic thrombus burden in patients with acute ST-segment elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention (pPCI). Methods: The study population consisted of 307 patients with STEMI. Baseline ECGs of the patients were analyzed for grade III ischemia; angiographic thrombus burden was assessed by thrombolysis in myocardial infarction thrombus classification. Results: A total of 108 (35%) patients had low thrombus burden whereas 199 (65%) patients had high thrombus burden. Grade III ischemia was more prevalent in patients with high thrombus burden (25.1% vs 11.1%, P = .004).Only grade III ischemia (odds ratio: 2.59, 95% confidence interval 1.24-5.39, P = .011) and history of coronary artery disease (CAD) were found to be the independent predictors of high thrombus burden. Conclusion: Grade III ischemia on ECG and previous history of CAD were independent predictors of coronary thrombus burden in patients with STEMI who underwent pPCI. © The Author(s) 2013.