Diclofenac spongious matrices based on collagen and alginate for relieving injury pains


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Drăghici R., Marin M. M., Ghica M. V., Kaya M. G. A., Anuța V., Dinu-Pîrvu C., ...More

7th International Conference on Advanced Materials and Systems, ICAMS 2018, Bucharest, Romania, 18 - 20 October 2018, pp.75-80, (Full Text)

  • Publication Type: Conference Paper / Full Text
  • Doi Number: 10.24264/icams-2018.i.10
  • City: Bucharest
  • Country: Romania
  • Page Numbers: pp.75-80
  • Keywords: Alginate, Collagen, Diclofenac
  • Open Archive Collection: AVESIS Open Access Collection
  • Hatay Mustafa Kemal University Affiliated: Yes

Abstract

The sport injuries become more and more frequent so there is a need to discover new solutions for increasing the quality of life for people affected by such wounds. The aim of this study was to obtain a novel NSAID drug delivery system, topical diclofenac spongious matrices based on collagen and alginate for the treatment of injuries and relieving of pain. The samples were analyzed by flow analysis and after their freeze-drying were analyzed by FT-IR and in vitro release of sodium diclofenac.The results obtained from analyses confirmed that diclofenac spongious matrices based on collagen and alginate exhibit proper characteristics for the treatment of injuries and relieving of pain.