Evaluation of the effects of zinc supplementation on the symptoms and duration of the disease in acute viral gastroenteritis


el ç., çelikkaya m. e.

Aile Hekimliği ve Palyatif Bakım, cilt.4, sa.1, ss.11-14, 2019 (Hakemli Dergi) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 4 Sayı: 1
  • Basım Tarihi: 2019
  • Dergi Adı: Aile Hekimliği ve Palyatif Bakım
  • Derginin Tarandığı İndeksler: TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.11-14
  • Hatay Mustafa Kemal Üniversitesi Adresli: Evet

Özet

Introduction: Acute viral gastroenteritis is the second most common cause of high morbidity and mortality in childhood. Viral gastroenteritisis the most common cause of severe diarrhea and associated hospitalizations especially in toddlers. It has been shown that the administration of 20mg of zinc daily during acute diarrhea reduces the duration of watery diarrhea by 25% and it has been reported to have protective and therapeuticeffects in the acute period. The aim of this study is to retrospectively determine the beneficial effects of oral zinc supplementation on the severityand duration of complaints of toddlers who were treated in our clinic with the diagnosis of acute viral gastroenteritis.Methods: Toddlers who were hospitalized in the Department of Pediatrics for acute viral gastroenteritis between October 2016 and March 2018were included in the study. The study was retrospective and the data of the patients were obtained from the patient files. The diagnosis of acuteviral gastroenteritis was made by detecting the adenovirus-rotavirus antigen in the fresh stool specimens. The patients were divided into twogroups. Group 1: patients who received zinc supplementation in addition to support treatment. Group 2: patients who received only supportivetherapy.Results: The mean number of vomiting was 3.60 / day and watery diarrhea was 5.20 / day in group-1 while number of vomiting was 6.1 / dayand watery diarrhea was 8.9 / day in group-2 in the 36th hour during treatment. The tolerability of oral feeding at 36 th hour was 49.39% ( 41) ingroup-1 and 45.07% (32) in group-2. The mean number of vomiting and watery diarrhea in group-1 cases at 72th hours was 1.2 / day and 4.30 /day, while in group-2 cases, 3.90 / day and 7.20 / day.Conclusions: Although the physiopathology of the effects of zinc on gastroenteritis is not yet fully understood, diarrhea is seen both as a causeand as a result of zinc deficiency. The fact that patients with gastroenteritis benefit from zinc support suggests that zinc enhances this effect byincreasing intestinal immunity.