Akademik Veri Yönetim Sistemi
Viral Hepatitis Journal, cilt.26, sa.2, ss.61-64, 2020 (ESCI)
Objectives: Intravenous drug use (IVDU) is more common inprisoner patients, and this is a global problem. Hepatitis C virus(HCV) infection is higher in prisoners than general population. Inour study, we aimed to examine the IVDU rates and direct-actingantiviral (DAA) treatment results of the prisoners who applied toHatay Mustafa Kemal University Clinic of Infectious Diseases.Materials and Methods: In our study, IVDU rates and HCVtreatment results of 85 prisoners who applied to Hatay MustafaKemal University Faculty of Medicine Clinic of Infectious Diseasesbetween January 2017 and December 2019 were retrospectivelyanalyzed. Treatment results were evaluated by performing modifiedintention to tract (mITT) and per protocol (PP) efficacy analysis,respectively.Results: The rate of IVDU was 37.7% in prisoners who werepositive for HCV. Although sustained virological response (SVR) ratewas 100% in PP analysis, SVR rate was determined as 80.5% inmITT analysis. Viral genotype 3 (41.6%) and genotype 4 (39%) werethe most common.Conclusion: However, data on HCV screening and treatment inprisons in Turkey is inadequate or too low. We think that with theuse of DAAs, patients’ compliance to treatment will increase, it is animportant step for HCV eradication and multicenter studies shouldbe conducted.