Archives of Gynecology and Obstetrics, vol.284, no.6, pp.1331-1337, 2011 (SCI-Expanded)
Objective: We compared the safety and effectiveness of oxytocin, dinoprostone and misoprostol for cervical priming. Study design: A total of 218 patients were enrolled to receive between one and three treatments according to physicians' options. The end points were: (1) vaginal delivery or Bishop score ≥8 at the end of 12 h, (2) vaginal delivery by 12 h or difference ≥4 between the initial and 12th hour Bishop scores. Statistical analyses were performed with ANOVA, Krustal Wallis, Scheffe, χ 2, Fisher, Advanced χ 2, and Kolmogorov-Smirnov tests. Tukey's HSD was used as a post hoc test. Results: Misoprostol showed statistical significance for the rate of vaginal delivery <12 h, ≥8 Bishop score at the end of 12 h, and cervical change of ≥4 Bishop scores within 12 h (p = 0.013). Conclusions: Comparison between cases Bishop score <4 showed that misoprostol is more effective than dinoprostone and oxytocin. Considering Bishop score = 0 cases we calculated no statistical significance. © Springer-Verlag 2011.