Chemical and biological evaluation of endemic <i>Origanum amanum</i> Post. essential oil
JOURNAL OF ESSENTIAL OIL RESEARCH, cilt.38, sa.2, ss.221-229, 2026 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 38 Sayı: 2
- Basım Tarihi: 2026
- Doi Numarası: 10.1080/10412905.2026.2620761
- Dergi Adı: JOURNAL OF ESSENTIAL OIL RESEARCH
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Compendex
- Sayfa Sayıları: ss.221-229
- Anahtar Kelimeler: anti-inflammatory, antimicrobial, antioxidant, oil composition, Oregano
- Hatay Mustafa Kemal Üniversitesi Adresli: Evet
Özet
Origanum amanum is an endemic species of the Lamiaceae, from the Amanous Mountains, T & uuml;rkiye. The plant samples were collected from Hatay, with soil samples from the same area. The chemical composition of the essential oil (EO) obtained by hydrodistillation was determined by gas chromatography-flame ionization detector and gas chromatography/mass spectrophotometry, simultaneously. In the essential oil, carvacrol was characterized as the main component at 63.7%. The in vitro antioxidant capacity of O. amanum oil was evaluated using ABTS center dot+ and DPPH center dot methods and antimicrobial activity was tested against Staphylococcus aureus ATCC 6538, Escherichia coli O157:H7 RSSK 234, Salmonella enterica subsp. enterica serovar Typhimurium ATCC 13,311, Candida krusei ATCC 6258, and Listeria monocytogenes ATCC 19111 pathogens. The in vitro 5-lipooxygenase (5-LOX) enzyme inhibition assay showed low anti-inflammatory activity. Good antioxidant capacity in the DPPH center dot assay, followed by inhibitory activity against S. aureus, E. coli, and S. Typhimurium pathogens, were observed.