Synthesis, characterization and antimicrobial activities of transition metal complexes of <i>N</i>,<i>N</i>-dialkyl-N′-(2-chlorobenzoyl)thiourea derivatives

Binzet G., Arslan H., Floerke U., Kuelcue N., DURAN N.

JOURNAL OF COORDINATION CHEMISTRY, cilt.59, sa.12, ss.1395-1406, 2006 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 59 Sayı: 12
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1080/00958970500512633
  • Dergi Adı: JOURNAL OF COORDINATION CHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1395-1406
  • Hatay Mustafa Kemal Üniversitesi Adresli: Evet

Özet

N, N-di-n-propyl-N'-(2-chlorobenzoyl) thiourea (HL1) (1), N, N-diphenyl-N'-(2-chlorobenzoyl) thiourea (HL2) (2), and their Ni-II, Co-II, Cu-II, Zn-II, Pt-II, Cd-II and Pd-II complexes have been synthesized and characterized. HL1 and its copper complex were characterized by single-crystal X-ray diffraction methods. The ligands coordinate as bidentates yielding essentially neutral complexes of the type [ML2]. The complexes were screened for their in vitro antibacterial, antifungal activities and toxicity. All compounds showed antimicrobial activity, but antibacterial efficacy is greater than antifungal activity.