Serum nitric oxide levels and flow-mediated dilatation in patients with Sheehan syndrome and the effect of combination therapy consisting of L-thyroxine, prednisolone, and conjugated estrogen/medroxyprogesterone acetate

Bahceci M., Pasa S., Akay H. O., Tuzcu A., TÜMER C., Gokalp D.

Fertility and Sterility, vol.89, no.4, pp.995-997, 2008 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 89 Issue: 4
  • Publication Date: 2008
  • Doi Number: 10.1016/j.fertnstert.2007.04.014
  • Journal Name: Fertility and Sterility
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.995-997
  • Hatay Mustafa Kemal University Affiliated: No

Abstract

Baseline and stimulated nitric oxide (NO) levels were higher, whereas baseline arterial diameter, FMD-stimulated NO increment, and arterial dilatation ratio were lower in Sheehan syndrome (SS) patients than in control subjects. After combination therapy consisting of prednisolone, L-thyroxine, and conjugated estrogen, baseline and stimulated NO levels of SS remained as high, but FMD-stimulated NO, NO increment ratio, and arterial dilatation ratio increased with treatment. © 2008 American Society for Reproductive Medicine.