Assessment of platelet-to-lymphocyte ratio in patients with retinal vein occlusion

KURTUL B. E., Çakmak A. İ., ELBEYLİ A., Özarslan Özcan D., Özcan S. C., Cankurtaran V.

Therapeutic Advances in Ophthalmology, cilt.12, 2020 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 12
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1177/2515841420971949
  • Dergi Adı: Therapeutic Advances in Ophthalmology
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Anahtar Kelimeler: inflammation, platelet-to-lymphocyte ratio, retinal vein occlusion, thrombus
  • Hatay Mustafa Kemal Üniversitesi Adresli: Evet

Özet

Purpose: To investigate platelet-to-lymphocyte ratio (PLR) in retinal vein occlusion (RVO) patients. Methods: In this study, we retrospectively reviewed data of 32 patients with RVO (RVO group) and 32 age- and sex-matched participants without RVO (control group) between January 2017 and March 2019. The PLR was determined by dividing the platelet count by the lymphocyte count. Results: Age and gender were comparable between the groups (p = 0.204 and p = 0.800, respectively). PLR was significantly elevated in the RVO group compared with the control group (137 (113–164) vs 101 (86–129), p = 0.001)). In the receiver operator characteristics curve analysis, the optimal cut-off value of PLR for predicting RVO was 123, with 69% sensitivity and 72% specificity. Conclusion: We report that PLR are elevated in RVO, suggesting that PLR may be a useful marker for RVO.