Eurasian Journal of Pulmonology, cilt.28, sa.1, ss.9-15, 2026 (ESCI, Scopus, TRDizin)
BACKGROUND AND AIM: Long-term oxygen therapy (LTOT) improves survival and outcomes in chronic respiratory failure. This multicenter study assesses the factors affecting adherence in patients undergoing long-term oxygen therapy and evaluates its impact on the frequency of hospital visits. METHODS: Clinical and demographic data of patients receiving LTOT who were admitted to the study centers between January 1 and June 30, 2024, were recorded. Patients who adhered to LTOT for ≥15 hours per day, including both daytime and nighttime use, were classified as fully adherent. Data from adherent patients were compared with those of non-adherent patients. Factors affecting LTOT adherence were determined using logistic regression analysis. RESULTS: Among the 374 patients who met the inclusion criteria, 40.6% were classified as adherent to LTOT. Emergency room visits (median: 3/year) and hospital admissions (median: 1/ year) were more frequent among LTOT-adherent patients over the past year. Regression analysis identified a body mass index (BMI) <25 kg/m2 and type 2 respiratory failure as independent predictors of LTOT adherence. Among patients with type 2 respiratory failure, those with a BMI <25 kg/m2 were found to be more likely to adhere to LTOT, with a specificity of 74.1% and a sensitivity of 44.9%. A reduction in the frequency of emergency room visits was observed in the group that adhered to LTOT for one year. CONCLUSIONS: A BMI <25 kg/m2 and type 2 respiratory failure can predict adherence to LTOT.