Menopausal cardiomyopathy: Does it really exist? A case-control deformation imaging study


Keskin Kurt R., Nacar A. B., Güler A., Silfeler D. B., Buyukkaya E., Karateke A., ...Daha Fazla

Journal of Obstetrics and Gynaecology Research, cilt.40, sa.6, ss.1748-1753, 2014 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 40 Sayı: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1111/jog.12368
  • Dergi Adı: Journal of Obstetrics and Gynaecology Research
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1748-1753
  • Anahtar Kelimeler: 2-D strain imaging, left ventricular function, menopause
  • Hatay Mustafa Kemal Üniversitesi Adresli: Evet

Özet

Aim We aimed to evaluate and compare the left ventricular (LV) functions of pre- and postmenopausal women at similar ages with none of the known cardiovascular risk factors, by both conventional and advanced echocardiographic methods such as 2-D strain imaging via speckle tracking echocardiography. Methods The study population consisted of 40 healthy postmenopausal women aged 45-50 years and 40 healthy premenopausal women of the same age group. None of the subjects had any cardiovascular risk factors and were on hormone replacement therapy. LV strain and strain rate parameters were measured by 2-D strain imaging. The main outcome measure was effect of menopause on LV function. Results There were no significant differences between the pre- and postmenopausal groups with regard to conventional echocardiographic parameters. LV longitudinal strain and LV early diastolic strain rate values were significantly lower in the postmenopausal group when compared to the premenopausal group. Also, there was a significant negative correlation between LV global strain and serum follicle-stimulating hormone (r = -0.349, P = 0.002). Conclusion Our study results demonstrated that healthy postmenopausal women had lower LV longitudinal strain values when compared to the healthy premenopausal women of the same age group by speckle tracking echocardiography. © 2014 The Authors. Journal of Obstetrics and Gynaecology Research © 2014 Japan Society of Obstetrics and Gynecology.