Akademik Veri Yönetim Sistemi
Journal of Clinical Periodontology, cilt.51, sa.3, ss.274-287, 2024 (SCI-Expanded)
Aim: The aim of the present cross-sectional study was to evaluate periodontal conditions and the association of periodontitis with oral-health-related quality of life (OHRQoL) in patients with a history of bipolar disorder. Materials and Methods: A total of 160 participants were recruited in four groups for the study: 40 patients with euthymic episodes, 40 patients with depression, 40 patients with manic episodes and 40 systemically healthy individuals. Clinical periodontal parameters were recorded. Oral Health Impact Profile (OHIP-14) was used to measure the impact of oral health on the quality of life. Results: Bipolar disorder groups exhibited generally higher clinical parameters compared with the control group (p <.05). OHIP-14 total score (β = 3.32, 95% confidence interval [CI]: 0.08–6.56, p =.044), functional limitation (β =.89, 95% CI: 0.27–1.49, p =.005) and physical pain (β =.64, 95% CI: 0.01–1.27, p =.046) were associated with bipolar depression episodes. Psychological discomfort was associated with the presence of generalized periodontitis (β =.76, 95% CI: 0.01–1.51, p =.047) and psychological disability was associated with the presence of stage III–IV (β =.83, 95% CI: 0.07–1.59, p =.033) and generalized (β =.75, 95% CI: 0.07–1.42, p =.029) periodontitis. Conclusions: According to this study, a history of bipolar disorder episodes (exposure) may be associated with increased prevalence and severity of periodontitis and related reported OHRQoL impacts (outcomes). Bipolar depression episodes had a higher impact on OHRQoL than other bipolar episodes.