Research Information System
Turkiye Klinikleri Dermatoloji, vol.25, no.1, pp.28-31, 2015 (Scopus)
T-cell acute lymphoblastic leukemia (T-ALL), derived from precursor T cell, is a hematologic malignancy which spreads over the extramedullary organs. Skin metastasis of leukemia; leukemia cutis, rarely seen in T-cell leukemia, is infiltration of skin by malign leukemic cells. A thirty-three years old woman who diagnosed as T-ALL one year ago was consulted to our department for skin lesions. In dermatological examination, erythematous brownish nodules and tumors were observed on her face, body and extremities. The lesions were evaluated as T-ALL skin involvement according to histopathological investigation. Chemotherapy was initiated to the patient. After treatment, noduler and tumoral lesions became smaller. However, the patient died because of sepsis. In conclusion, T-ALL which is a malignant hematological disease characterized by bone marrow and internal organ involvement rarely metastases to the skin. Skin involvement of T-ALL indicates poor prognosis. We present this case who has widespread skin lesions because it is rarely seen.