History Studies, cilt.13, sa.4, ss.1357-1368, 2021 (Hakemli Dergi)
The Seleucids, the dominant power in theMesopotamian geography of the Early HellenisticPeriod, began to fall short in the administration of theEastern lands after their founding king, SeleucusNicator I. This inadequacy was especially related to theefforts of the Parthians, one of the centralist structuresestablished after the Persians in Ancient Iran, to gainstrength and establish themselves politically inMesopotamia. It has been understood that the Parthiansbegan to be politically organized during the Seleucidperiod when the Persian State was accepted as one ofthe important centers and administered by thegovernors appointed by the Seleucids. The greatresistance of the Parthians against Antiochus Megas IIIin 205 BC and the agreement made with the Seleucidsas a result of this resistance enabled the Parthians to beregistered as a regional political power in the East. . Inan effort to maintain these gains against the Seleucids,the Parthians had the opportunity to expand theirpolitical sphere of activity with the withdrawal of theSeleucids from Babylon and Iran in 130/129 BC due tothe changing political balances and internal rebellionsduring the reign of Antiochus VII. In the period whenthe Seleucids struggled with Rome for the westernlands and lost this struggle, the Parthians had tostruggle with Rome as a powerful kingdom inMesopotamia after the Seleucids. In this study, whichaims to chronologically examine the existencestruggles of the Parthians and Seleucids inMesopotamian geography, ancient records of theperiod and modern literature were used.