Kocatepe Veterinary Journal, cilt.18, sa.2, ss.104-111, 2025 (TRDizin)
The aim of this study was to investigate the effects of prepartum Vitamin E, Selenium and Melatonin treatments on uterineinvolution in Awassi sheep. The study included a total of 24 ewes with singleton pregnancies. Fifteen days before their expecteddelivery, ewes were randomly divided into three groups. Group VE (n=8) received Vitamin E and Selenium intramuscularly.Group M (n=8) received a subcutaneous ear implant containing 18 mg of melatonin. Group C (n=8) served as the controlgroup and received no treatment. The mean time for completion of uterine involution in Group VE, Group M, and Group Cwere 20.57±1.21; 19.13±1.13; 18.67±1.09 days, respectively (p>0.05). Uterine diameters were 9.66±0.59; 9.54±0.35; 7,95±0.22in Group VE, Group M, and Group C, respectively. Uterine diameters in Group VE and Group M were significantly greaterthan Group C on Day 3 of postpartum (p<0.05). Mean outer caruncular diameters were 1.93±0.10; 1.60±0.10; 1.65±0.07 inGroup VE, Group M, and Group C. respectively. Mean outer caruncular in Group VE were significantly greater than GroupM and Group C (p<0.05). Mean outer caruncular diameters were greater on Day 3 compared to Day 6 regardless of groups(p<0.05). Mean inner caruncular diameters were greater on Day 3 compared to Day 6 regardless of groups (p<0.05). Therewas no differences in terms of mean inner caruncular diameters between groups (p>0.05). In conclusion, it was found thatprepartum administration of Vitamin E, Selenium and Melatonin had no significant effects on the completion time ofpostpartum uterine involution on Awassi ewes.Keywords: Melatonin, Selenium, Sheep, Uterine Involution, Vitamin E The aim of this study was to investigate the effects of prepartum Vitamin E, Selenium and Melatonin treatments on uterine involution in Awassi sheep. The study included a total of 24 ewes with singleton pregnancies. Fifteen days before their expected delivery, ewes were randomly divided into three groups. Group VE (n=8) received Vitamin E and Selenium intramuscularly. Group M (n=8) received a subcutaneous ear implant containing 18 mg of melatonin. Group C (n=8) served as the control group and received no treatment. The mean time for completion of uterine involution in Group VE, Group M, and Group C were 20.57±1.21; 19.13±1.13; 18.67±1.09 days, respectively (p>0.05). Uterine diameters were 9.66±0.59; 9.54±0.35; 7,95±0.22 in Group VE, Group M, and Group C, respectively. Uterine diameters in Group VE and Group M were significantly greater than Group C on Day 3 of postpartum (p<0.05). Mean outer caruncular diameters were 1.93±0.10; 1.60±0.10; 1.65±0.07 in Group VE, Group M, and Group C. respectively. Mean outer caruncular in Group VE were significantly greater than Group M and Group C (p<0.05). Mean outer caruncular diameters were greater on Day 3 compared to Day 6 regardless of groups (p<0.05). Mean inner caruncular diameters were greater on Day 3 compared to Day 6 regardless of groups (p<0.05). There was no differences in terms of mean inner caruncular diameters between groups (p>0.05). In conclusion, it was found that prepartum administration of Vitamin E, Selenium and Melatonin had no significant effects on the completion time of postpartum uterine involution on Awassi ewes.