Immunohistochemical characterization of perineal melanoma in Kilis goats


Ozyildiz Z., Ceylan C., Yilmaz R., Ozsoy S.

Biotechnic and Histochemistry, cilt.87, sa.6, ss.408-412, 2012 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 87 Sayı: 6
  • Basım Tarihi: 2012
  • Doi Numarası: 10.3109/10520295.2012.679366
  • Dergi Adı: Biotechnic and Histochemistry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.408-412
  • Anahtar Kelimeler: Histopathology, Immunocytochemistry, Kilis goat, Melanoma, Perineum
  • Hatay Mustafa Kemal Üniversitesi Adresli: Evet

Özet

We describe the clinical, histopathological and immunohistochemical features of the malignant melanomas in the perineal regions of Kilis goats from Sanliurfa province in Turkey. We studied 13 female Kilis goats between 3 and 8 years old that were brought to Harran University Veterinary School, Department of Surgery, between 2002 and 2010. By macroscopic examination, the masses were determined to have elastic consistency, dark brown-black color, necrotic surfaces and ulceration. Microscopically, pleomorphic cells were observed under the basal layer and these advanced toward the dermis. These cells were polyhedral, round or spindle-shaped, anaplastic, and their cytoplasm contained varying amounts of dark brown-black pigments. Immunohistochemical staining was obtained with anti-melan A, vimentin and S100 antibodies. © 2012 The Biological Stain Commission.