Fractal and lacunarity analysis of trabecular bone changes in odontogenic cysts on panoramic radiographs


BELGIN H. B., AKTUNA BELGİN C., ICEN M.

Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology, 2026 (ESCI, Scopus) identifier identifier

Özet

Objective: The aim of this study is to evaluate the effectiveness of fractal analysis (FA), and lacunarity analysis (LA) in the identification and differential diagnosis of odontogenic cysts. Methods: A retrospective analysis included panoramic radiographs from 210 patients (107 females, 103 males; mean age: 32.0 ± 10.9 years), categorized equally into three groups based on pathology: radicular cysts (n = 70), dentigerous cysts (n = 70), and odontogenic keratocysts (n = 70). Two distinct Regions of Interest were selected from each image: one representing the cystic area (case) and one from the adjacent healthy trabecular bone (control). Each region of interest underwent filtering (Gaussian blur, subtraction from original) and conversion into a binary skeletonized image for quantitative analysis, and the identically processed images were subsequently utilized for LA. Results: In all three cyst groups, the FA values of the Control group were found to be significantly higher than the Case group (p < 0.001), however, no statistically significant difference was observed between the Control and Case groups in LA values (p > 0.05). In the Control group, there were no statistically significant differences among the three cysts groups regarding either FA or LA (p > 0.05). In the Case group, the mean FA value of the dentigerous cysts group was significantly lower than the other cysts (p < 0.001), while LA values no show a significant distinction (p > 0.05). Conclusions: Fractal analysis demonstrated significant differences between healthy and cystic bone, suggesting its potential utility in non-invasive assessment of odontogenic cyst behavior. However, LA alone may not provide additional diagnostic value.