Predictors of chronic total occlusion in nonculprit artery in patients with acute coronary syndrome: Mean platelet volume and uric acid

Kurtul A., Yarlioglues M., Murat S. N., Celik I. E., DEMİRÇELİK M. B., Ocek A. H., ...Daha Fazla

Angiology, cilt.66, sa.6, ss.553-559, 2015 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 66 Sayı: 6
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1177/0003319714542998
  • Dergi Adı: Angiology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.553-559
  • Anahtar Kelimeler: acute coronary syndrome, chronic total occlusion, mean platelet volume, noninfarct-related artery, serum uric acid
  • Hatay Mustafa Kemal Üniversitesi Adresli: Hayır

Özet

Chronic total occlusion (CTO) in a noninfarct-related artery (non-IRA) is an independent predictor of mortality in acute coronary syndrome (ACS). Mean platelet volume (MPV) and serum uric acid (SUA) are associated with cardiovascular events in ACS. We investigated the relationship between the presence of non-IRA-CTO with MPV and SUA levels in patients with ACS. Patients (n = 1024) who underwent urgent coronary angiography for ACS were included in this study. Blood samples were drawn on admission. Patients were categorized into 2 groups: non-IRA-CTO (-) and non-IRA-CTO (+). The MPV and SUA levels on admission were significantly higher in the non-IRA-CTO (+) group than in the non-IRA-CTO (-) group (P <.001). At multivariate analysis, MPV (odds ratio [OR]: 4.705, P <.001) and SUA (OR: 2.535, P <.001) were independent predictors of non-IRA-CTO together with age, hemoglobin, ejection fraction, and non-ST-segment elevation ACS. The MPV and SUA levels were significant and independent predictors for the presence of non-IRA-CTO in patients with ACS.