Akademik Veri Yönetim Sistemi
REVISTA CIENTIFICA-FACULTAD DE CIENCIAS VETERINARIAS, cilt.35, sa.1, 2025 (SCI-Expanded, Scopus)
The objective of this study is to examine the expression levels of ezrin and moesin proteins from a molecular and immunohistochemical standpointABS RACTfollowing the administrationof terebinth oil in rats with ovarian ischemia-reperfusion injury. Atotal of32femaleSprague-Dawley rats wereutilized inthe methoate (DMT) pesticide is one of the chem cals used to otectome agiculturalareasfromharmful organisms. DMT study. The rats were randomly assigned to one of four groups, with eight rats ineach group: control,ischemia, I/R, and I/R+ sidues re eased directly or indirect y to the environment terebinth oil. Following the induction of torsion, the treatment group received 2 ml.kg-1 of terebinth oil orally via gavage onc use serious problems in nature DMT residues mixed with the daily for 28 d. At the conclusionof theexperiment, ovarian tis uatic enviro ment adversely affect aquatic organ sms and is effect is carried tohumans through the foodcha n. In th s sues were obtained for immunohistochemical and molecular udy, oxiative stress responsesindced by DMT pesticide in analysis. The immunohistochemical evaluation demonstrated a positiveezrin expressionwereinepithelialinvestigated.cellsForwithinthisthe purpose I/R+terebinth oil group, in comparison to the I/R group. Converse idative st ess and ant ox dant parameters Thiobarb turic acid acive substances (TBARS) Glutathion (GSH)Sueroxide ly, a negative reaction was observed in the vicinity of blood smutas (SOD) catalase (CAT) and glutathione peroxidase vessels. The expression of moesin was observed to be positive in granulosa cells and stromal areas.Additionally, a notable PX) caused b dimethoat DMT) icide decline in the expression levels ofezrin and moesin proteins y ( pest n17 1 wasobserved in the treatment group incomparison to the .5, 35, and 70 mg L concentrations at 24 and 96 hours ere inve tgate.Resultswere determined usingELISA kis damage group. Moreover, the administration of terebinth oil was observed to result in protein expression levels that were more closely aligned with those observed in the control group. ere observedbetweendecreases in CATandGPx actiities and The present study has demonstrated the impact of terebinth creases in TBARS evels SPSS 24 0package program one way oil administration on the expression levels of ezrin and moesin NOVA (D proteins in a model of ovarian ischemia-reperfusion injury.