Assessment of Red Cell Distribution Width, Platelet/lymphocyte Ratio, Systemic Immune-inflammation Index, and Neutrophil/lymphocyte Ratio Values in Patients with Central Retinal Artery Occlusion

ELBEYLİ A., KURTUL B. E., Ozcan D. O., Ozcan S. C., Dogan E.

Ocular Immunology and Inflammation, cilt.30, sa.7-8, ss.1940-1944, 2022 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 30 Sayı: 7-8
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1080/09273948.2021.1976219
  • Dergi Adı: Ocular Immunology and Inflammation
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • Sayfa Sayıları: ss.1940-1944
  • Anahtar Kelimeler: blood cell count, Central retinal artery occlusion, Inflammation, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, red cell distribution width, systemic immune-inflammation index
  • Hatay Mustafa Kemal Üniversitesi Adresli: Evet

Özet

Purpose: To evaluate complete blood count (CBC)-derived inflammatory indices in central retinal artery occlusion (CRAO). Methods: A total of 42 patients with CRAO (CRAO group) and 42 age- and sex-matched subjects without CRAO (Control group) were included. CBC parameters including red cell distribution width (RDW) levels were assayed. Platelet/lymphocyte ratio (PLR), systemic immune-inflammation index (SII) and neutrophil/ lymphocyte ratio (NLR) were calculated. Results: RDW, PLR, SII and NLR values were significantly higher in CRAO group than control group [15.2 ± 1.47% vs 13.96 ± 1.13% (p <.001), 127.94 ± 48.21 vs 101.16 ± 24.84 (p =.008), 667.11 ± 357.84 vs 493.44 ± 207.07 (p =.008), 2.70 ± 1.27 vs 2.13 ± 0.83 (p =.018), respectively]. In multivariate analysis only RDW was independent predictor for CRAO (OR 2.317, p <.001). On ROC analysis, area under curve of RDW, PLR, SII, and NLR for CRAO were 0.761, 0.685, 0.622 and 0.618, respectively. Conclusion: RDW seems superior to other inflammatory indices to predict CRAO.